Socio-Economic Status and Childhood Leukemia in California

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چکیده

The role of socio-economic status (SES) in the development of childhood leukemia remains poorly understood. To elucidate this association, some studies used maternal or paternal education, occupation, or family income as proxies for individual-level SES [2-6]. Other studies have used community-level SES, for example, census tract or ward-based socio-economic characteristics, e.g. income, population density, rent, employment, communitylevel occupational class, and social deprivation score [7-12]. A small number of studies have looked at SES at both individual and community levels [13-15]. Poole at al. reviewed literature on SES and childhood leukemia and concluded that in studies using individual-level measures (family income, mother’s and father’s education) that required some subject contact, lower SES was linked to higher risk of leukemia [16]. In contrast, in record-based studies using father’s occupational class and in ecologic studies using community-level occupational class, higher SES was associated with higher risk of childhood leukemia. The authors suggested that these apparent contradictions may have resulted from differences in design and/or SES measure, but could not distinguish between these two hypotheses. One study by McMahon (1962), used medical payment status as a proxy measure for SES to examine mortality data from 1947 to 1960 [17]. Two other studies used the source of payment for prenatal care as a proxy for SES in research on preterm birth [18-19].

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تاریخ انتشار 2015